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History of Clenbuterol Poisonings. In 2022, hundreds of people in the Mexican state of Yucatán were thought to have fallen ill after ingesting meat from animals who had been raised with clenbuterol, and in 2011, clenbuterol-tainted meat from Shuanghui (now WH Group, Smithfield’s current owner) sickened 1,700 people and killed one in China. Abstract Clenbuterol, a beta-agonist, was determined in samples of beef liver and muscle. The method employed an acidic aqueous extraction followed by protein precipitation. The supernatant liquid was passed through a weak cation-exchange cartridge and then through a commercially available immunoaffinity cartridge. Clenbuterol was the most commonly detected β-agonists in meat products. However, clenbuterol was less frequently detected in lamb than in beef, and it was not detected in lamb samples. In contrast, salbutamol was detected more frequently in lamb than in beef. Clenbuterol is and illegal growth promoterillegally used in farms to fatten up animals before sending them to slaughter. In recent news Tour de France winner Alberto Contador has been tested positive for clenbuterol. Clenbuterol can also be used as a sport enhancement drug and is banned by the World Anti-Doping Agency. While more than a quarter of the sellers interviewed claim to know of suppliers for horse meat, only 7% would like to sell horse meat. Yet, 10% of the 433 samples tested positive for horse meat. The proportions of raw and cooked beef samples containing horse meat were similar at 9. The presence of clenbuterol in beef sausages could represent a risk of unintentional doping in sport field, because the clenbuterol is a banned substance included in the World Anti‐Doping Agency's (WADA) list of prohibited substances. Keywords: clenbuterol, meat products, UHPLC–MS/MS, unintentional doping, veterinary residues Go to: Abstract
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